As with other local anesthetics, transient Central Nervous System reactions characterized by nervousness, dizziness, blurred vision, nausea, and tremors or convulsions may occur. Drowsiness merging into unconsciousness and respiratory arrest are the manifestations of toxicity. Treatment of patients consists of assuring and maintaining a patient's airway, supporting ventilation with oxygen, and assisted or controlled respiration as required. Should convulsions persist despite ventilatory therapy, small increments of anticonvulsive agents may be given intravenously. Examples of such agents include a benzodiazepine, an ultra-short acting barbiturate, or a short-acting barbiturate. Cardiovascular depression may require circulatory assistance with intravenous fluids and/or vasopressors as dictated by the clinical situation.